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Cytokines and Joint Injury (Progress in Inflammation Research) [Hardcover]

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Item Number 223236  
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Item description for Cytokines and Joint Injury (Progress in Inflammation Research) by Wim B. van den Berg...

This topical insight in the role of cytokines in joint inflammation and joint destruction is important for a better understanding of key processes in diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Apart from the impact of well-known and novel cytokines on joint tissues, the various chapters address the issue of targeted therapy with biological response modifiers and future interventions with carefully designed inhibitors. Special attention is given to elements of synovial cell activation, cell-cell interaction, cytokine interplay as well as mechanisms of cartilage destruction and bone erosion. New information on the novel cytokines IL-15, IL-17 and IL-18 and their position in the complex cytokine interplay is provided, in addition to an outline of the role of established cytokines, such as TNF, IL-1 and IL-6. Cytokine regulation of destructive enzymes, RANKL, the endogenous inhibitor OPG and their crucial roles as central players in joint erosion are highlighted. This volume gives a complete and balanced view on pivotal cytokines and joint pathology for the biomedical and clinical researcher.

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Item Specifications...

Pages   295
Est. Packaging Dimensions:   Length: 9.2" Width: 6.4" Height: 0.9"
Weight:   1.8 lbs.
Binding  Hardcover
Release Date   Jul 12, 2004
Publisher   Birkhäuser Basel
ISBN  3764370017  
ISBN13  9783764370015  

Availability  136 units.
Availability accurate as of Oct 23, 2016 08:14.
Usually ships within one to two business days from La Vergne, TN.
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Product Categories

1Books > Subjects > Health, Mind & Body > Disorders & Diseases > Nervous System
2Books > Subjects > Medicine > Basic Science > Immunology
3Books > Subjects > Medicine > Basic Science > Microbiology
4Books > Subjects > Medicine > General
5Books > Subjects > Medicine > Pharmacology > General
6Books > Subjects > Professional & Technical > Medical > Basic Sciences > Immunology
7Books > Subjects > Professional & Technical > Medical > Basic Sciences > Microbiology
8Books > Subjects > Professional & Technical > Medical > Medicine > Surgery > Orthopedics
9Books > Subjects > Professional & Technical > Medical > Pharmacology > Pharmacology

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