Item description for Combining Targeted Biological Agents With Radiotherapy: Current Status and Future Directions by William Small...
Combining Targeted Biological Agents with Radiotherapy: Current Status and Future Directions is an overview of the current state of clinical and pre-clinical research in combining radiotherapy with targeted biological agents to fight cancer. The text provides a general overview of targeted agents, reviews the current clinical trials, and includes a look at the future of this state-of-the-art practice. This book begins with a general overview of the topic, including an introduction to the subject; the basic science rationale behind the two most important current targeted agents: epidermal growth factor (EGFR) receptors and vascular epithelial growth factor (VEGF) receptors; the dermatologic manifestations of targeted agents; and an introduction to radioimmunotherapy-a treatment that has the ability to combine targeted agents directly with radiotherapy. The second half of the book focuses on specific disease sites, including malignant gliomas, head and neck, lung, pancreatic, cervical, and endometrial cancers.
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Est. Packaging Dimensions: Length: 10" Width: 7.2" Height: 0.7" Weight: 1.3 lbs.
Release Date Jun 6, 2008
Publisher Demos Medical Publishing
ISBN 1933864346 ISBN13 9781933864341
Availability 102 units. Availability accurate as of Jan 17, 2017 10:40.
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Reviews - What do customers think about Combining Targeted Biological Agents With Radiotherapy: Current Status and Future Directions?
There are many discrepancies, typos and errors Aug 28, 2008
The book by its title is very appealing; however after reading the list of contributors/chapters for three days I realize that the different areas/chapters are overlapping in scientific context without providing a clear understanding of the molecular mechanisms involved in targeted biological agents and radiation. The book provides (describes) the current use of monoclonal antibodies and inhibitors in cancer therapy but does not give a understanding of the actual additive or synergetic effects of radiation and biological effectors at the level of the tumor microenvironment; furthermore, it barely describes the potential adverse events that can be encountered in the use of this combinatorial strategies.
I was very disappointed that the book was not proof read before publication. There are many typos and discrepancies. For example, in the list of contributors, the term VEGF is described as Vascular Epithelial Growth Factor. Even though the endothelium, the inner lining of blood vessels, is a specialized form of epithelium, the definition is just incorrect.