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Some Industrial Chemicals Volume 77 (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans) [Paperback]

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Item description for Some Industrial Chemicals Volume 77 (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans) by UNAIDS...

Evaluates or re-evaluates the carcinogenic risks to humans posed by exposure to sixteen organic industrial chemicals. These included some aromatic amines (ortho-toluidine, 4-chloro-ortho-toluidine, and 5-chloro-ortho-toluidine), some ethanolamines (di- and triethanolamine and N-nitrosodiethanolamine), and three esters [di(2-ethylhexyl) phthalate (DEHP), di(2-ethylhexyl) adipate, and cinnamyl anthranilate]. Seven of the sixteen compounds were evaluated in previous IARC Monographs and are reconsidered here in the light of new evidence.
Three chemicals were classified or reclassified as probably carcinogenic to humans: ortho-toluidine, 4-chloro-ortho-toluidine, and glycidol. Four compounds, evaluated here for the first time, namely 2,2-bis(bromomethyl)propane-1,3-diol, 2,3-dibromopropan-1-ol, ethylbenzene, and nitromethane, were classified as possibly carcinogenic to humans. N-Nitrosodiethanolamine, which can readily be formed from either di- or triethanolamine in the presence of inorganic nitrite, remained classified as possibly carcinogenic to humans.
For eight compounds, including 5-chloro-ortho-toluidine, coumarin, pyridine, diethanolamine, triethanolamine, di(2-ethylhexyl) adipate, and cinnamyl anthranilate, evidence was judged inadequate to classify these compounds according to their carcinogenicity in humans.
The most extensive monograph is devoted to an evaluation of di(2-ethylhexyl) phthalate (DEHP), which had previously been classified as possibly carcinogenic to humans. Using assessment criteria recently established for compounds that induce peroxisome proliferation in the liver, the evaluation downgraded DEHP to the group of compounds that cannot be classified. Two other compounds that cause peroxisome proliferation, di(2-ethylhexyl) adipate and cinnamyl anthranilate, were also evaluated as not classifiable as to carcinogenicity to humans.

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Item Specifications...

Studio: World Health Organization
Pages   564
Est. Packaging Dimensions:   Length: 10" Width: 7" Height: 1.18"
Weight:   2.17 lbs.
Binding  Softcover
Publisher   World Health Organisation
ISBN  9283212770  
ISBN13  9789283212775  

Availability  125 units.
Availability accurate as of Oct 28, 2016 02:26.
Usually ships within one to two business days from La Vergne, TN.
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10Books > Subjects > Science > Chemistry > Industrial & Technical
11Books > Subjects > Science > General
12Books > Subjects > Science > Technology > Risks

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