Newsletter   Secure Checkout   Shopping Cart (0 Items)  
Search:    Welcome Guest! Save up to 30-40% on most items with our awesome everyday discounts!

Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors [Paperback]

Our Price $ 71.44  
Retail Value $ 76.00  
You Save $ 4.56  
Item Number 218461  
Buy New $71.44
Available on the Internet only.

Item description for Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors by Tobias Noeske...

Group I metabotropic glutamate receptors (mGluRs) play an important role in the treatment of numerous neurodegenerative, cognitive and psychiatric disorders. How can we identify exogenous ligands mediating the effects of mGluRs? How do these ligands affect the receptor? The author Tobias Noeske presents the establishment of strategies for the identification and optimization of molecules acting as non-competitive antagonists of group I mGluRs. These strategies ensure high diversity in the identified chemotypes not resembling original reference molecules ("scaffold-hopping"). The detection of new scaffolds, in turn, is divided into two approaches: First the development of pharmacological assays to screen compounds at a certain target for their bioactivity, and second the evaluation of computer aided methods for the identification of virtual hits to be screened on the pharmacological assays. Promising molecules were optimized regarding bioactivity and selectivity, their binding mode investigated and, finally, compared to existing lead compounds. This book addresses scientists in academia and industry working in early stage drug discovery, predominantly in computer aided drug design.

Promise Angels is dedicated to bringing you great books at great prices. Whether you read for entertainment, to learn, or for literacy - you will find what you want at!

Item Specifications...

Pages   204
Est. Packaging Dimensions:   Length: 9.61" Width: 6.69" Height: 0.43"
Weight:   0.73 lbs.
Binding  Softcover
Release Date   Aug 10, 2007
Publisher   VDM Verlag Dr. Mueller e.K.
ISBN  3836423375  
ISBN13  9783836423373  

Availability  61 units.
Availability accurate as of Oct 25, 2016 08:38.
Usually ships within one to two business days from La Vergne, TN.
Orders shipping to an address other than a confirmed Credit Card / Paypal Billing address may incur and additional processing delay.

More About Tobias Noeske

Register your artisan biography and upload your photo! Are You The Artisan or Author behind this product?
Improve our customers experience by registering for an Artisan Biography Center Homepage.

Product Categories

1Books > Subjects > Medicine > Basic Science > Genetics
2Books > Subjects > Medicine > General
3Books > Subjects > Medicine > Specialties > Pathology > Laboratory Medicine
4Books > Subjects > Professional & Technical > Medical > Basic Sciences > Genetics
5Books > Subjects > Professional & Technical > Medical > Medicine > Internal Medicine > Pathology > Laboratory Medicine

Reviews - What do customers think about Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors?

Be the first to write a review about Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors

Ask A Question or Provide Feedback regarding Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors

Item Feedback and Product Questions
For immediate assistance call 888.395.0572 during the hours of 10am thru 8pm EST Monday thru Friday and a customer care representative will be happy to help you!

Help us continuously improve our service by reporting your feedback or questions below:

I have a question regarding this product
The information above is incorrect or conflicting
The page has misspellings or incorrect grammar
The page did not load correctly in my browser or created an error.

Email Address:
Anti Spam Question. To combat spammers we require that you answer a simple question.
What color is the sky?
Leave This Blank :
Do Not Change This Text :

Add This Product Widget To Your Website

Looking to add this information to your own website? Then use our Product Widget to allow you to display product information in a frame that is 120 pixels wide by 240 pixels high.

    Copy and paste the following HTML into your website and enjoy!

Order toll-free weekdays 10am thru 10pm EST by phone: 1-888-395-0572 (Lines are closed on holidays & weekends.)
Customer Service | My Account | Track My Orders | Return Policy | Request Free Catalog | Email Newsletter

Gift Certificates
RSS Feeds
About Us
Contact Us
Terms Of Use
Privacy Policy