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Pharmacology of Neurotransmitter Release (Handbook of Experimental Pharmacology) [Hardcover]

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Item description for Pharmacology of Neurotransmitter Release (Handbook of Experimental Pharmacology) by Thomas C. Südhof...

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book's second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.

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Item Specifications...

Pages   582
Est. Packaging Dimensions:   Length: 9.45" Width: 6.22" Height: 1.1"
Weight:   2.2 lbs.
Binding  Hardcover
Release Date   Jan 8, 2008
Publisher   Springer
ISBN  3540748040  
ISBN13  9783540748045  

Availability  119 units.
Availability accurate as of Oct 23, 2016 06:27.
Usually ships within one to two business days from La Vergne, TN.
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Product Categories

1Books > Subjects > Medicine > General
2Books > Subjects > Medicine > Internal Medicine > Neurology > Neuroscience
3Books > Subjects > Medicine > Pharmacology > General
4Books > Subjects > Professional & Technical > Engineering > Bioengineering > Biomedical Engineering
5Books > Subjects > Professional & Technical > Medical > Medicine > Internal Medicine > Neurology > Neuroscience
6Books > Subjects > Professional & Technical > Medical > Pharmacology > Pharmacology
7Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biochemistry
8Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biology > Cytology
9Books > Subjects > Science > Biological Sciences > Anatomy
10Books > Subjects > Science > Biological Sciences > Biochemistry
11Books > Subjects > Science > Biological Sciences > Biology > Cell Biology
12Books > Subjects > Science > General

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