Item description for Some Thyrotropic Agents (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans) by The International Agency for Research on Cancer...
This volume evaluates carcinogenicity to humans of 19 chemicals that are carcinogenic to the thyroid follicular-cell epithelium in rodents. These include some so-called anti-thyroid drugs (methimazole, methylthiouracil, propylthiouracil and thiouracil); some sedatives (doxylamine succinate and phenobarbital); and some other drugs including the systemic antifungal antibiotic griseofulvin, the diuretic spironolactone, and the antibacterial sulfa drugs sulfamethazine and sulfamethoxazole. Other chemicals are or have been used in agriculture as pesticides (amitrole, chlordane/heptachlor, hexachlorobenzene and toxaphene), in foods and cosmetics (kojic acid), in hair dyes (2,4-diaminoanisole) or as industrial chemicals (N,N-diethylthiourea, ethylenethiourea and thiourea). Five of the 19 chemicals (N,N- diethylthiourea, doxylamine succinate, kojic acid, methimazole and sulfamethazine) were evaluated for the first time. From the available epidemiological studies, there was no indication of excess thyroid cancer risk in humans exposed to any of these agents.
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Studio: World Health Organization
Est. Packaging Dimensions: Length: 9.2" Width: 6.8" Height: 1.7" Weight: 2.9 lbs.
Publisher World Health Organisation
ISBN 9283212797 ISBN13 9789283212799
Availability 54 units. Availability accurate as of Jan 17, 2017 07:11.
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More About The International Agency for Research on Cancer
The International Agency for Research on Cancer (IARC) is part of the World Health Organization. IARC's mission is to coordinate and conduct research on the causes of human cancer, the mechanisms of carcinogenesis, and to develop scientific strategies for cancer control. The Agency is involved in both epidemiological and laboratory research and disseminates scientific information through publications, meetings, courses, and fellowships.