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The Hereditary Basis of Allergic Diseases (Progress in Inflammation Research) [Hardcover]

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Item description for The Hereditary Basis of Allergic Diseases (Progress in Inflammation Research) by Stephen T. Holgate...

Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.

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Item Specifications...

Pages   191
Est. Packaging Dimensions:   Length: 9.1" Width: 6.4" Height: 0.6"
Weight:   1.35 lbs.
Binding  Hardcover
Release Date   Sep 17, 2002
Publisher   Birkhäuser Basel
ISBN  3764364025  
ISBN13  9783764364021  

Availability  92 units.
Availability accurate as of May 22, 2017 11:07.
Usually ships within one to two business days from La Vergne, TN.
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More About Stephen T. Holgate

Register your artisan biography and upload your photo! STEPHEN T. HOLGATE, MD, DSc, FRCP, is Medical Research Council Professor of Immunopharmacology and Honorary Consultant Physician at Southampton University Hospital Trust. He is the Chairman of Science Council s Science in Health Group, as well as a member of Royal Commission on Environmental Pollution. His research works have focused on cellular and mediator mechanisms of allergy and asthma, with specific emphasis on applications to diagnosis and treatment. S. T. Holgate is the Co-editor of "Clinical and Experimental Allergy", in addition to being on the editorial board of over 25 journals. He has published over 800 peer-reviewed papers besides editing more than 50 books on asthma.

Stephen T. Holgate currently resides in Southhampton. Stephen T. Holgate has an academic affiliation as follows - Clinical Professor of Immunopharmacology, Southampton General Hospital.

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Product Categories

1Books > Subjects > Health, Mind & Body > Disorders & Diseases > Allergies
2Books > Subjects > Medicine > Diseases > General
3Books > Subjects > Medicine > General
4Books > Subjects > Medicine > Internal Medicine
5Books > Subjects > Medicine > Pharmacology > Pharmacy
6Books > Subjects > Professional & Technical > Medical > Basic Sciences > Genetics
7Books > Subjects > Professional & Technical > Medical > Pharmacology > Pharmacy
8Books > Subjects > Professional & Technical > Professional Science > Evolution > Genetics
9Books > Subjects > Science > Biological Sciences > Biology > General
10Books > Subjects > Science > Evolution > Genetics

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