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Complement and Kidney Disease (Progress in Inflammation Research) [Hardcover]

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Item description for Complement and Kidney Disease (Progress in Inflammation Research) by Peter F. Zipfel...

It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.

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Item Specifications...

Pages   236
Est. Packaging Dimensions:   Length: 9.1" Width: 6.3" Height: 0.8"
Weight:   1.45 lbs.
Binding  Hardcover
Release Date   Dec 22, 2005
Publisher   Birkhäuser Basel
ISBN  3764371668  
ISBN13  9783764371661  

Availability  108 units.
Availability accurate as of Oct 28, 2016 03:55.
Usually ships within one to two business days from La Vergne, TN.
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1Books > Subjects > Medicine > Basic Science > Immunology
2Books > Subjects > Medicine > Basic Science > Microbiology
3Books > Subjects > Medicine > Basic Science > Physiology
4Books > Subjects > Professional & Technical > Medical > Basic Sciences > Immunology
5Books > Subjects > Professional & Technical > Medical > Basic Sciences > Microbiology
6Books > Subjects > Science > Biological Sciences > Anatomy
7Books > Subjects > Science > General

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