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Phylogenetic Analysis of Viral Quasispecies [Paperback]

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Item description for Phylogenetic Analysis of Viral Quasispecies by Patricia Buendia...

A new approach in the analysis of viral evolution is presented in this book, an approach that merges Phylogenetic analysis and Bioinformatic techniques. Patterns of viral evolution are inferred from serially-sampled sequence data, i.e., sequence data obtained from strains isolated at consecutive time points from a single patient or host. Traditional phylogenetic methods assume a tree-like evolutionary model, while many RNA viruses have the capacity to exchange genetic material with one another using a process called recombination. A genealogy involving recombination is best described by a network structure. A more general approach was implemented in a new computational tool, Sliding MinPD, one that is mindful of the sampling times of the input sequences and that reconstructs the viral evolutionary relationships in the form of a network structure with implicit representations of recombination events. The underlying network organization reveals unique patterns of viral evolution and could help explain the emergence of disease-associated mutants and drug-resistant strains, with implications for patient prognosis and treatment strategies.

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Item Specifications...

Pages   212
Est. Packaging Dimensions:   Length: 9.61" Width: 6.69" Height: 0.45"
Weight:   0.76 lbs.
Binding  Softcover
Release Date   Jan 7, 2008
Publisher   VDM Verlag Dr. Mueller e.K.
ISBN  383643458X  
ISBN13  9783836434584  

Availability  92 units.
Availability accurate as of Oct 23, 2016 11:46.
Usually ships within one to two business days from La Vergne, TN.
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Product Categories

1Books > Subjects > Medicine > Basic Science > Microbiology
2Books > Subjects > Medicine > General
3Books > Subjects > Professional & Technical > Medical > Basic Sciences > Microbiology
4Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biology > Biology
5Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biology > Microbiology
6Books > Subjects > Science > Biological Sciences > Biology > General
7Books > Subjects > Science > Biological Sciences > Biology > Microbiology

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