Item description for Platelets, Thrombosis and the Vessel Wall (Advances in Vascular Biology) by Michael C Berndt...
Unstable angina, myocardial infarction, and stroke, precipitated by thrombosis, are the leading causes of death in the western world. In response to such vascular trauma, platelets rapidly adhere to the exposed subendothelial matrix. Platelet activation through agonist and adhesion receptors leads to a cascade of intracellular events including cytoskeletal reorganization and secretion of platelet dense bodies, ultimately resulting in platelet aggregation. Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis. The volume covers areas such as platelet production, interaction of platelets with leucocytes, and mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.
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Studio: CRC Press
Est. Packaging Dimensions: Length: 9.92" Width: 6.88" Height: 0.96" Weight: 2.08 lbs.
Release Date Apr 17, 2000
ISBN 9057023695 ISBN13 9789057023699