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Protein Structural Domain Boundary Prediction - A Mixture of Experts Approach [Paperback]

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Item description for Protein Structural Domain Boundary Prediction - A Mixture of Experts Approach by Ian M. MacDonald...

The prediction of protein structural domains and their boundaries from amino acid sequence data is an open problem of interest to the bioinformatics community. Determining a protein's structural domains experimentally can be very difficult. The assignment of structural domains relies on the time-consuming process of determining the three-dimensional structure. There is a strong potential for computational methods to aid in this and other tasks in structural molecular biology. Efforts from other researchers, along with the results presented here indicate that boundaries can indeed be predicted from amino acid sequence alone. A new machine-learning based architecture is introduced to predict structural domain boundaries, the key feature of which is a Mixture of Experts (MoE) model. The MoE provides the ability to combine the predictions of individual classifiers, such as artificial neural networks, support vector machines, and nave Bayes classifiers, so as to optimize prediction accuracy. This book is addressed to students and researchers in both computer science and bioinformatics.

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Item Specifications...

Pages   216
Est. Packaging Dimensions:   Length: 9.61" Width: 6.69" Height: 0.46"
Weight:   0.77 lbs.
Binding  Softcover
Release Date   Feb 6, 2008
Publisher   VDM Verlag Dr. Mueller e.K.
ISBN  3836437201  
ISBN13  9783836437202  

Availability  61 units.
Availability accurate as of Oct 24, 2016 11:59.
Usually ships within one to two business days from La Vergne, TN.
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Product Categories

1Books > Subjects > Computers & Internet > Computer Science > Software Engineering > Information Systems
2Books > Subjects > Computers & Internet > General
3Books > Subjects > Science > Biological Sciences > Bioinformatics

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