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Drug Discovery and Evaluation: Pharmacological Assays [Hardcover]

By H. Gerhard Vogel (Editor)
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Item description for Drug Discovery and Evaluation: Pharmacological Assays by H. Gerhard Vogel...

The rapid progress in biology will continue to change the methodological approach to drug discovery in the coming years. Electronic media will continuously help researchers to access and share information. It is, however, becoming more and more evident that many young pharmacologists have only limited training in classical pharmacological methodologies. These long-standing and still highly relevant methods are simply not available in the electronic databases. Drug Discovery and Evaluation:Pharmacological Assays bridges this gap by comprehensively covering the pharmacological methods that have been utilized successfully for more than a hundred years as well as the latest technologies.

The classical methods and the newest technologies, all in one book!

The 3rd edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described.

For this third edition, all existing chapters have been revised and completely updated. A large number of assays were added: we are now publishing two volumes. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis (formerly called activity of blood constituents), - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity.

Audience: Pharmacologists and Pharmacists in Academia and Industry

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Item Specifications...

Pages   1844
Est. Packaging Dimensions:   Length: 3.5" Width: 8" Height: 10.5"
Weight:   12.6 lbs.
Binding  Hardcover
Release Date   Nov 20, 2007
Publisher   Springer
ISBN  3540714200  
ISBN13  9783540714200  

Availability  0 units.

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Product Categories

1Books > Subjects > Medicine > General
2Books > Subjects > Medicine > Pharmacology > General
3Books > Subjects > Medicine > Pharmacology > Pharmacy
4Books > Subjects > Professional & Technical > Medical > Pharmacology > Pharmacology
5Books > Subjects > Professional & Technical > Medical > Pharmacology > Pharmacy
6Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biochemistry
7Books > Subjects > Science > Biological Sciences > Biochemistry

Reviews - What do customers think about Drug Discovery and Evaluation: Pharmacological Assays?

Well constructed and potentially useful  Sep 15, 2005
I have the 2nd edition of this reference, obtained in 2003. Springer-Verlag and their printers have done a very nice job of making this large (1400-page) book, and they provide a very readable typeset. The text is laid out in numerous short application notes describing different pharmacological assays, and these include sections on the study's purpose, a paragraph on the procedure, another on the approach to interpreting results, a fourth cursory section discussing modifications of the method by others, and a usually generous list of references after that. A big plus, I think, is the inclusion of a CD-ROM that contains an Adobe PDF of the entire text. This is a better medium in which to do searching, especially since the hardcover's printed lookup is set up in such extensive run-in indexing, with numerous cascades of indented em-dashes on subentries that it is really kind of annoying. The Contents list, grouped by organ systems, is a lot more useful.

It's still a difficult call making a decision to recommend a text like this - if you are actively doing pharmacological research, your sources are probably more current at your bench, or in recent journals and meetings. But, the very readable structure, many references, and a useful CD-ROM, suggests Vogel's text as an appealing and well-assembled package for academic and group reference.
A wonderful book for pharmacological Researchers  Jun 29, 2000
The book is a wonderful addition to books on drug evaluation. I feel pharmacologists are getting very few books on this subject. This book can end up the search for such pharmacologists. It will surely boost the research in this field. I hope that this book should reach into hands of every pharmacologists. Whether he/she is a academician or researcher, this book will be a valuable addition to his/her personal library. Each institute conducting research or teaching in pharmacology should also have this book in the library.

Many thanks to the authors and publishers of this books.


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