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Drug Discovery and Evaluation [Hardcover]

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Item description for Drug Discovery and Evaluation by Hans G. Vogel...

Now expanded and updated to include molecular biology and genetic engineering techniques! The 2nd edition of this successful reference book contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic respiratory, renal and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. The enclosed and fully searchable CD-ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.

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Item Specifications...

Pages   1250
Est. Packaging Dimensions:   Length: 10.9" Width: 7.9" Height: 2.4"
Weight:   6.25 lbs.
Binding  Hardcover
Release Date   Aug 5, 2002
Publisher   Springer
ISBN  3540423966  
ISBN13  9783540423966  

Availability  0 units.

More About Hans G. Vogel

Register your artisan biography and upload your photo! H. Gerhard Vogel is a licenced Pharmacist and Physician (Universities of Erlangen and TA1/4bingen, Germany). He taught as Professor of Pharmacology and Toxicology at the Universities Marburg and Frankfurt. He joined Research at the pharmaceutical company Hoechst AG, Frankfurt, to become Head of Endocrinology, Head of the Department of Pharmacology, and the Head of International Preclinical Evaluation and Development. His latest position was Head of the Decision Board on Pharmaceutical Development. At present, he is working as a Consultant for Pharmaceutical and Medical Research and Development.

His scientific work was devoted to the elaboration of new pharmacological methods, pharmacology of plant extracts from various countries, pharmacology of steroid hormones, pharmacology of peptide hormones, pharmacology of cardiac glycosides, biomechanics and biochemistry of connective tissue, experimental gerontology, experimental dermatology, and development procedures for pharmaceutical products. H. Gerhard Vogel has published more than 160 papers, mainly on new pharmacological methods, on endocrinology (in particular peptide endocrinology), biomechanics and biochemistry of connective tissue, such as skin and bone, and on other topics. He is a member of many international and national scientific societies and a co-editor and contributor to several scientific textbooks.

Together with Wolfgang H. Vogel he published the first edition of Drug Discovery and Evaluation: Pharmacological Assays (Springer-Verlag Berlin Heidelberg New York) in 1997. The second completely revised, updated and enlarged edition with many contributions by his colleagues was published in 2002. The thirdedition of that work will appear in late 2007. He is also Editor-in-Chief of the book Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays, which was published at Springer as well.

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10Books > Subjects > Science > Biological Sciences > Biochemistry

Reviews - What do customers think about Drug Discovery and Evaluation?

Well constructed and potentially useful  Sep 15, 2005
I have the 2nd edition of this reference, obtained in 2003. Springer-Verlag and their printers have done a very nice job of making this large (1400-page) book, and they provide a very readable typeset. The text is laid out in numerous short application notes describing different pharmacological assays, and these include sections on the study's purpose, a paragraph on the procedure, another on the approach to interpreting results, a fourth cursory section discussing modifications of the method by others, and a usually generous list of references after that. A big plus, I think, is the inclusion of a CD-ROM that contains an Adobe PDF of the entire text. This is a better medium in which to do searching, especially since the hardcover's printed lookup is set up in such extensive run-in indexing, with numerous cascades of indented em-dashes on subentries that it is really kind of annoying. The Contents list, grouped by organ systems, is a lot more useful.

It's still a difficult call making a decision to recommend a text like this - if you are actively doing pharmacological research, your sources are probably more current at your bench, or in recent journals and meetings. But, the very readable structure, many references, and a useful CD-ROM, suggests Vogel's text as an appealing and well-assembled package for academic and group reference.
A wonderful book for pharmacological Researchers  Jun 29, 2000
The book is a wonderful addition to books on drug evaluation. I feel pharmacologists are getting very few books on this subject. This book can end up the search for such pharmacologists. It will surely boost the research in this field. I hope that this book should reach into hands of every pharmacologists. Whether he/she is a academician or researcher, this book will be a valuable addition to his/her personal library. Each institute conducting research or teaching in pharmacology should also have this book in the library.

Many thanks to the authors and publishers of this books.


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