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Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems [Hardcover]

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Item description for Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems by Gerd Gellissen...

While the choices of microbial and eukaryotic expression systems for production of recombinant proteins are many, most researchers in academic and industrial settings do not have ready access to pertinent biological and technical information since it is normally scattered throughout the scientific literature. This book closes the gap by providing information on the general biology of the host organism, a description of the expression platform, a methodological section---with strains, genetic elements, vectors and special methods, where applicable---as well as examples of proteins produced with the respective platform. The systems thus described are well balanced by the inclusion of three prokaryotes (two Gram-negatives and one Gram-positive), four yeasts, two filamentous fungi and two higher eukaryotic cell systems---mammalian and plant cells. Throughout, the book provides valuable practical and theoretical information on the criteria and schemes for selecting the appropriate expression platform, the possibility and practicality of a universal expression vector, and on comparative industrial-scale fermentation, with the production of a recombinant Hepatitis B vaccine chosen as an industrial example.

With a foreword by Herbert P. Schweizer, Colorado State University, USA:

"As a whole, this book is a valuable and overdue resource for a varied audience. It is a practical guide for academic and industrial researchers who are confronted with the design of the most suitable expression platform for their favorite protein for technical or pharmaceutical purposes. In addition, the book is also a valuable study resource for professors and students in the fields of applied biology and biotechnology."

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Item Specifications...

Pages   426
Est. Packaging Dimensions:   Length: 9.53" Width: 6.93" Height: 1.02"
Weight:   2.12 lbs.
Binding  Hardcover
Release Date   Feb 11, 2005
Publisher   Wiley-VCH
ISBN  3527310363  
ISBN13  9783527310364  

Availability  0 units.

More About Gerd Gellissen

Register your artisan biography and upload your photo! Gerd Gellissen is Senior Scientist at Rhein Biotech GmbH, Dusseldorf and Associate Professor of Microbiology at the Heinrich-Heine University of Dusseldorf.
He has published approximately 130 research papers and co-authored 7 patents. Professor Gellissen is editor of the Wiley-VCH book "Hansenula polymorpha" (2002).

Gerd Gellissen has an academic affiliation as follows - Aachen, Germany formerly Rhein Biotech GmbH, D?sseldorf, Germany Aache.

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Product Categories

1Books > Foreign Language Books > German > All German Books
2Books > Foreign Language Books > German > Nonfiction
3Books > Foreign Language Books > German > Professional & Technical
4Books > Subjects > Medicine > Special Topics > Biotechnology
5Books > Subjects > Professional & Technical > Engineering > Bioengineering > Biotechnology
6Books > Subjects > Professional & Technical > Engineering > General
7Books > Subjects > Professional & Technical > Medical > Basic Sciences > Biotechnology
8Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biotechnology
9Books > Subjects > Science > Biological Sciences > Biotechnology
10Books > Subjects > Science > Chemistry
11Books > Subjects > Science > General

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