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Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy [Hardcover]

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Item Number 231602  
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Item description for Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy by Dieter Marmé...

Tumor angiogenesis is one of the most prominent mechanisms driving tumor development and progression. In the past 30 years some of the most important signaling pathways linking specific angiogenic activities of tumor cells to fatal reactions of the patient s vascular system have been elucidated. Crucial targets for therapeutic intervention have been identified and validated.

Based on these achievements targeted drug development programs have been implemented to interfere with tumor angiogenesis as an attractive strategy in cancer treatment. The first targeted anti-angiogenic drugs have been approved for a variety of solid metastasizing cancers.

Part 1 describes the basic mechanisms. Tumor-angiogenic signaling pathways are presented as new potential targets for anti-angiogenic therapy. Part 2 reviews the efforts made to validate new targets and to show efficacy in animals. Part 3 is devoted to the clinical development of the novel anti-angiogenic drugs and their use in clinical practice.

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Item Specifications...

Pages   845
Est. Packaging Dimensions:   Length: 9.69" Width: 7.95" Height: 1.65"
Weight:   4.85 lbs.
Binding  Hardcover
Release Date   Dec 6, 2007
Publisher   Springer
ISBN  354033176X  
ISBN13  9783540331766  

Availability  60 units.
Availability accurate as of Oct 22, 2016 08:02.
Usually ships within one to two business days from La Vergne, TN.
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Product Categories

1Books > Calendars > Astrological
2Books > Subjects > Medicine > Basic Science > Biochemistry
3Books > Subjects > Medicine > General
4Books > Subjects > Medicine > Internal Medicine > Oncology > General
5Books > Subjects > Medicine > Pharmacology > General
6Books > Subjects > Professional & Technical > Medical > Basic Sciences > Biochemistry
7Books > Subjects > Professional & Technical > Medical > Medicine > Internal Medicine > Oncology
8Books > Subjects > Professional & Technical > Medical > Pharmacology > Pharmacology

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