Item description for Protein Folding Kinetics: Biophysical Methods by Bengt Nölting...
Protein Folding Kinetics - Biophysical Methods (2nd Edition) gives a deep insight into the principles and concepts of the kinetic and structural resolution of fast chemical and biophysical reactions of proteins with emphasis on protein-folding reactions. The study of fast protein-folding reactions and the understanding of the folding paradox have significantly advanced due to the recent development of new biophysical methods which allow not only kinetic resolution in the sub-millisecond time scale but also structural resolution with unprecedented precision. Pathways and structures of early and late folding events and the transition state structures of fast- and ultrafast-folding proteins can now be studied in far more detail. Important techniques include biophysical, chemical, molecular biological and mathematical methods, in particular protein engineering, Phi-value analysis, time-resolved circular dichroism, optical triggers and pulsed infrared LASER methods, pressure and temperature jump, ultrafast mixing, stopped flow and quenched flow, dielectric relaxation and electric-field-jump, acoustic relaxation, fluorescence- and isotope-labeling, H/D exchange methods, NMR line broadening and stopped-flow NMR, transition state theory, solutions of rate equations, and evolutionary computer programming. Protein Folding Kinetics - Biophysical Methods is written for students and researchers in biochemistry, biophysics, and related fields.
Special features in the second edition:
-Includes detailed information and 12 color figures on the high resolution of folding transition states.
-Discusses structural determinants of the rate of protein folding on a timescale from microseconds to seconds.
-Provides information on self-evolving computer programs for protein-folding simulations and protein-structure predictions.
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Est. Packaging Dimensions: Length: 9.3" Width: 5.9" Height: 0.6" Weight: 1.35 lbs.
Release Date Sep 29, 2005
ISBN 3540272771 ISBN13 9783540272779
Availability 127 units. Availability accurate as of Mar 27, 2017 08:46.
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Reviews - What do customers think about Protein Folding Kinetics: Biophysical Methods?
Useful and up-to-date Sep 23, 2004
To my mind, Nolting's book is the best one in the field of protein folding. This book is a very useful source for biochemistry students. It is excellent, comprehensive and precise.
An excellent resource for biochem / biophys students Oct 3, 2000
Students and faculty alike have attested to the extraordinary usefulness of Nolting's book of the high resolution of rapid reaction kinetics. The book was really help me learn why protein folding is such a highly efficient process, and which extremely advanced methods have become available to study biophysical and chemical reaction kinetics not only in the millisecond, microsecond and picosecond time range, but also with amazingly high structural resolution. The graphics were great and provided me with plenty of information about numerous biological and biophysical methods, in particular protein engineering, DNA cloning and site-directed mutagenesis, Phi-value analysis, NMR, circular dichroism, fluorescence, pulsed LASER spectroscopy, temperature jumping, ultrafast mixing, stopped-flow, dielectric relaxation, acoustic relaxation, and pressure jump techniques. If you want to learn or teach modern biophysical methods ... this is the book of your choice.