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Bioinformatics [Hardcover]

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Item description for Bioinformatics by Andrzej Polanski...

Bioinformatics as a discipline arose out of the need to introduce order into the massive data sets produced by the new technologies of molecular biology: large-scale DNA sequencing, measurements of RNA concentrations in multiple gene expression arrays, and new profiling techniques in proteomics. As such, bioinformatics integrates a number of traditional quantitative sciences such as mathematics, statistics, computer science and cybernetics with biological sciences such as genetics, genomics, proteomics and molecular evolution.

In this comprehensive textbook, Polanski and Kimmel present mathematical models in bioinformatics and they describe the biological problems that inspire the computer science tools used to handle the enormous data sets involved. The first part of the book covers the mathematical and computational methods, while the practical applications are presented in the second part. The mathematical presentation is descriptive and avoids unnecessary formalism, and yet remains clear and precise. Emphasis is laid on motivation through biological problems and cross applications. Each of the four chapters in the first part is accompanied by exercises and problems to support an understanding of the techniques presented. Each of the six chapters of the second part is devoted to some specific application domain: sequence alignment, molecular phylogenetics and coalescence theory, genomics, proteomics, RNA, and DNA microarrays. Each chapter concludes with a problems and projects section, to deepen the reader's understanding and to allow for the design of derived methods. Many of the projects involve publicly available software and/or Web-based bioinformatics depositories. Finally, the book closes with a thorough bibliography, reaching from classic research results to very recent findings, providing many pointers for future research.Overall, this volume is ideally suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on its mathematical and computer science background.

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Item Specifications...

Pages   376
Est. Packaging Dimensions:   Length: 9.29" Width: 6.14" Height: 1.02"
Weight:   1.74 lbs.
Binding  Hardcover
Release Date   May 29, 2007
Publisher   Springer
ISBN  3540241663  
ISBN13  9783540241669  

Availability  122 units.
Availability accurate as of Oct 25, 2016 03:19.
Usually ships within one to two business days from La Vergne, TN.
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Product Categories

1Books > Subjects > Computers & Internet > General
2Books > Subjects > Professional & Technical > Professional Science > Biological Sciences > Biology > Biology
3Books > Subjects > Science > Biological Sciences > Bioinformatics
4Books > Subjects > Science > Biological Sciences > Biology > General
5Books > Subjects > Science > General
6Books > Subjects > Science > Technology > General & Reference

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